发布时间：2017-07-25 10:01:27

PF-04979064产品描述：PF-04979064 is a potent and selective PI3K/mTOR dual kinase inhibitor with an IC(50) of 9.1nM.target：PI3KIC50：9.1nM.PF-04979064 exhibited excellent in vitro potency, very good solubility, high LipE, excellent kinome selectivity,24 robust PK/PD correlation and TGI efficacy, .........【阅读全文】

发布时间：2017-07-25 10:01:02

SQ22536产品描述：SQ22536 is an effective adenylate cyclase (AC) inhibitor.IC50 & Target: adenylate cyclase (AC)[1] In Vitro: SQ22536 (SQ22,536) effectively inhibits the effect of forskolin with respective IC50 values of 5 μM.Preincubation with graded concentrations of SQ22536 reveals that both SQ2.........【阅读全文】

发布时间：2017-07-25 10:00:37

F16产品描述：F16 is a small molecule that selectively inhibits proliferation of mammary epithelial, neu-overexpressing cells, as well as a variety of mouse mammary tumor and human breast cancer cell lines. 1, F16 induced cell cycle arrest in sensitive mouse tumor and human cancer cell lines.2, Pro.........【阅读全文】

发布时间：2017-07-25 10:00:12

NVP-BAW2881产品描述：BAW2881 is a potent and selective VEGFR inhibitor (vascular endothelial growth factor receptor tyrosine kinase inhibitor) with activity to inhibit chronic and acute skin inflammation.target: VEGFRIC 50: 37 nmol/LIn vitro: BAW2881 block VEGF-A-induce proliferation, migration, .........【阅读全文】

发布时间：2017-07-25 09:59:46

SHP099 (hydrochloride)产品描述：SHP099 hydrochloride is a potent, selective, orally available SHP2 inhibitor with an IC50 of 70 nM.IC50 & Target: IC50: 70 nM (SHP2)[1] In Vitro: The X-ray co-crystal for SHP099 with SHP2 reveals a new interaction with the basic amine and the Phe113 backbone carbonyl.........【阅读全文】