发布时间：2017-07-21 08:57:26

Aloxistatin产品描述：Aloxistatin (E64d) is a broad-spectrum cell-permeable cysteine protease inhibitor.IC50 & Target: Cysteine protease[1] In Vitro: Inhibition of protease-resistant prion protein (PrP-res) accumulation in ScNB cells by cysteine protease inhibitor Aloxistatin (E64d) with IC50 of 0.5.........【阅读全文】

发布时间：2017-07-21 08:55:23

SKF89976A (hydrochloride)产品描述：SKF89976A hydrochloride is a selective GABA transporter (GAT-1) inhibitor with IC50s of 0.28 μM, 137.34 μM and 202.8 μM for GAT-1, GAT-2 and GAT-3 in CHO cells, respectively.IC50 & Target: IC50: 0.28 μM (GAT-1), 137.34 μM (GAT-2), 202.8 μM (GAT-3)[1] In Vitr.........【阅读全文】

发布时间：2017-07-20 15:38:02

CZ415产品描述：CZ415 is a potent and highly selective mTOR inhibitor.IC50 & Target: mTOR[1]IC50: 14.5 nM (pS6RP), 14.8 nM (pAKT), 226 nM (IFNγ)[1] In Vitro: Inhibition of phosphorylation for both downstream targets results in 14.5 nM IC50 for pS6RP and 14.8 nM for pAKT. The immunosuppressive effe.........【阅读全文】

发布时间：2017-07-20 15:37:32

AM-2394产品描述：AM-2394 is a structurally distinct glucokinase activator (GKA). AM-2394 activates glucokinase (GK) with an EC50 of 60 nM.IC50 & Target: EC50: 60 nM (glucokinase)[1] In Vivo: AM-2394, a structurally distinct glucokinase activator that displays a robust reduction in plasma glucose du.........【阅读全文】

发布时间：2017-07-20 15:37:01

GSK6853产品描述：GSK6853 is a potent and selective inhibitor of the BRPF1 bromodomain. shows excellent BRPF1 potency (pKd 9.5) andgreater than 1600-fold selectivity over all other bromodomainstested.target: BRPF1.[1]In vivo: The ip route of administration would be suitable for dosing GSK6853 in .........【阅读全文】