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2013-10-09 15:21:01

Furthermore, DISH Networks made acounterbid for Clearwire totaling $3.30 per share and offering $2.2 billion for 24% of Clearwire's spectrum holdings, which could sway Clearwire completely away from Sprint or force Sprint to spend even more on acquiring a cashburning business. Conceptually, targeting inhibition of this protein thought to be vital to cancer cell growth should result in cancer cell death. While that sounds great on paper, we're in about the third inning of a nineinning game, and retaspimycin (formerly IPI504) is only in midstage trials for the treatment of nonsmallcell lung cancer, yet investors have priced Infinity as if approval is a certainty and we're on track to hit peak sales of the drug.

Beyond retaspimycin, Infinity has three ongoing trials for its PI3K inhibitor program, covering asthma, rheumatoid arthritis, and bloodborne malignancies, but only one has even reached midstage trials. In Infinity's most recent quarterly update, we learned that the company does have ample cash to conduct its trials well into 2015, but we're also staring down cash burn of $115 million to $125 million this year.

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