A lifelong diet rich in omega 3 fatty acids can inhibit growth of breast cancer tumours by 30 per cent
, according to new research from the University of Guelph.
The study, published recently in the Journal of Nutritional Biochemistry
, is believed to be the first to provide unequivocal evidence that omega 3s reduce cancer risk.
show that lifelong exposure to omega 3s has a beneficial role in disease prevention in this case, breast cancer prevention. What important is that we have proven that omega 3s are the driving force and not something else.
Breast cancer remains the most common form of cancer in women worldwide and is the second leading cause of female cancer deaths.
Advocates have long believed diet may significantly help in preventing cancer. But epidemiological and experimental studies to back up such claims have been lacking, and human studies have been inconsistent, Ma said.
are inherent challenges in conducting and measuring diet in such studies
, and it has hindered our ability to firmly establish linkages between dietary nutrients and cancer risk, he said.
we used modern genetic tools to address a classic nutritional question.
For their study
http://www.asmallheaven.net/replica-porsche-design-disocunt-uk.html, the researchers created a novel transgenic mouse that both produces omega 3 fatty acids and develops aggressive mammary tumours. The team compared those animals to mice genetically engineered only to develop the same tumours.
model provides a purely genetic approach to investigate the effects of lifelong omega 3s exposure on breast cancer development, Ma said.
our knowledge, no such approach has been used previously to investigate the role of omega 3s and breast cancer.
Mice producing omega 3s developed only two thirds as many tumours and tumours were also 30 per cent smaller as compared to the control mice.
difference can be solely attributed to the presence of omega 3s in the transgenic mice that significant, Ma said.
fact that a food nutrient can have a significant effect on tumour development and growth is remarkable and has considerable implications in breast cancer prevention.
Known as an expert in how fats influence health and disease, Ma hopes the study leads to more research on using diet to reduce cancer risk and on the benefits of healthy living.
is an area of growing importance. We are working to build a better planet, and that includes better lifestyle and diet, he said.
long term consequences of reducing disease incidence can have a tremendous effect on the health care system.
Funding for this research came from the Canadian Breast Cancer Research Alliance/Canadian Institutes of Health Research, the Canada Foundation for Innovation and the Ontario Research Fund.
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